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Key feature: Cachexia is a common systemic wasting condition with high morbidity and mortality associated with many diseases, including cancers and infections
Cachexia is associated with decreased survival in cancer patients and has a prevalence of up to 80%
Cancer cachexia is characterized by a negative energy balance, muscle and adipose tissue wasting, insulin resistance, and systemic inflammation
Because of its strong negative impact on prognosis and its multifactorial nature that is still not fully understood, cachexia remains an essential challenge in the field of cancer treatment
Cachexia prevalence was highest in pancreatic cancer (66.7%), followed by ovarian cancer (25%), lung cancer (20.8%), and breast cancer (17.3%)
Excessive weight loss after a severe illness such as cancer characterizes cachexia
see also:
Blood vessels
Cachexia/Cancer Cachexia, & Gut Microbiota