The uraemic toxins phenylacetylglutamine and indoxyl sulfate, previously reported in association with cardiovascular disease (Nemet et al. 2020 Cell 180: 862-877) and chronic kidney disease (Hung et al. 2017 J. Am. Heart Assoc. 6(2): e005022) were driven by a species from the Lachnospiraceae familyBar et al. 2020