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Macrophages (CD68s) & NFKB Signaling / NFKB Pathway

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Contents

NFKB activation leads to


  • activation and maturation

  • chemokine induction

  • cytokine induction

  • ROS generation

  • M1 and M2 plasticity (cell specific problems for quantitative investigation given)

  • PAMPs, DAMPs ligand discrimination (cell specific problems for quantitative investigation given)

  • tolerance versus trained immunity (cell specific problems for quantitative investigation given)


Aqdas & Sung 2023 Trends in Immunology 44(1): 32