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is triggered by humanin (HN)
The Phosphatidylinositol 3-kinases / Phosphoinositide 3-kinase (PI3K) is activated by G protein-coupled receptors (GPRCs) and tyrosine kinase receptors (RTK). PI3K catalyzes the phosphorylation of the 3'-OH position on the inositol ring of specific [phospholipids](brain://v…