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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Tumor-associated macrophages (TAMs) & Tumor microenvironment (TME)

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Tumor-associated macrophages (TAMs) & Tumor microenvironment (TME)

Glucose enters tumor cells via Glucose transporter 1 (GLUT1) and generates pyruvate via glycolysis, which is further converted to lactate via Lactate dehydrogenase A (LDHA). Intracellular lactate is transported into the Tumor Microenvironment (TME) via [SLC16A3 / Monocarboxyla…

Effects of glycolysis on the polarization and function of tumor-associated macrophages (Review)
Cao et al. 2023 Int. J. of Oncology 62(6):
Review
Re-education of macrophages as a therapeutic strategy in cancer
Kowal et al. 2019
Review
Tumor-associated macrophages: potential therapeutic strategies and future prospects in cancer
Li et al. 2021a
Review

4/13/2026