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Environmental chemical exposure significantly contributes to the development of cholestasis and nonalcoholic steatohepatitis (NASH).
Taylor et al. 2022 Drug Metab Dispos 50: 456-467
The development of the gut microbiome remains easily influenced by environmental factors until around three years of age
It is now well recognized that environmental factors, either directly or indirectly, have a decisive role in perinatal maturation of the mucosal immune system
The worldwide adiposity / obesity epidemic is stimulating efforts to identify host and environmental factors that affect energy balance