Plasmablast / Plasma cells

Plasma cells arise from B cells / B Lymphocytes when they have come into contact with antigen (differentiation). Their role is the secretion of antibodies.

Antibody-secreting plasma cells (PCs), on the other hand, depend on the activation of PR domain zinc finger protein 1 (Blimp-1) for their terminal differentiation
Bortnick & Murre 2016 Wiley Interdiscip Rev Dev Biol 5(2): 136-149
Tellier & Nutt 2019 Eur J Immunol 49(1): 30-37

The gut microbiome can influence the bone marrow microenvironment through cytokines. Plasma cells have Interleukin-17 (IL-17) receptors and are activated by Interleukin-17 Family / Interleukin-17 (IL-17) both in vitro and in vivo.
Prabhala et al. 2010 Blood 115: 5385-92

Interleukin-17 Family / Interleukin-17 (IL-17) affects the bone marrow microenvironment by increasing the expression of receptor activator of nuclear factor kappa-B ligand on stromal cells, which in turn stimulates osteoclasts, potentially resulting in the formation of bone lesions.
Noonan et al. 2010 Blood 116: 3554-63

see also:
B cells / B Lymphocytes
Gut microbiota & Multiple Myeloma (MM) / Plasmocytoma
Interleukin-17 Family / Interleukin-17 (IL-17) & Tumor growth