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Glucocorticoid-induced tumor necrosis factor receptor (GITR)

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The glucocorticoid-induced tumor necrosis factor receptor (GITR) is a member of the TNF receptor superfamily (TNFRSF), playing a crucial role in the immune system's response to tumors and infections. GITR is primarily expressed on various immune cells, including T cells, B cells, and natural killer (NK) cells, and is notably upregulated on regulatory T cells (Tregs) and effector T cells upon activation
Koon et al. 2016 J Clin Oncol 34: 3017-3017
He et al. 2021d J Clin Hepatol 37(7): 1718-1723