meRfi®-GM
Toll-like receptor 5 (TLR-5)
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Toll-like receptor 5 (TLR-5) is known to recognize bacterial flagellin from invading mobile bacteria
The agonist flagellin leads to dimerization. The two adapter molecules, TIR domain-containing adapter protein (TIRAP) and Myeloid Differentiation Primary Response 88 (MYD88) are activated. Receptor-associated MyD88 recruits [Interleukin-1 receptor-associated kinase 4 (IRAK4)](brain:/…