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Colonocyte maturation and differentiation require PPAR-gamma (peroxisome proliferator-activated receptor-gamma) (), a nuclear receptor highly expressed in differentiated colonocytes of mice and humans
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) triggers mitochondrial beta-oxidation of long-chain and short-chain fatty acids (SCFAs), which leads to oxygen consumption through [oxida…