meRfi®-GM
Colonocytes / Colonic Epithelial Cells
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Contents
Colonocyte maturation and differentiation require PPAR-gamma (peroxisome proliferator-activated receptor-gamma) (), a nuclear receptor highly expressed in differentiated colonocytes of mice and humans
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) triggers mitochondrial beta-oxidation of long-chain and short-chain fatty acids (SCFAs), which leads to oxygen consumption through [oxida…
References (Sources)
- Activation of autophagy and PPARγ protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation
- Dysbiotic Proteobacteria expansion: a microbial signature of epithelial dysfunction
- Hypoxia-Inducible Factor 1–Dependent Induction of Intestinal Trefoil Factor Protects Barrier Function during Hypoxia
- Peroxisome proliferator-activated receptor gamma is induced during differentiation of colon epithelium cells
- PPARγ Modulates Long Chain Fatty Acid Processing in the Intestinal Epithelium
- Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man
- The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon