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Broad-spectrum antibiotics have the potential to alter the microbiome, which can increase susceptibility to pathogens (2, 3). This includes the risk of colonization by drug-resistant 'ESKAPE' pathogens such as Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp (4). Additionally, these antibiotics may promote [inflammatory diseases](brain://3VG7PG5860yl…