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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Regulatory T Cells (Tregs)

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Regulatory T Cells (Tregs) play a critical role in suppressing tissue inﬂammation through the release of cytokines such as TGF beta , IL-10 and IL-35
Su et al. 2022 Cells 11: 2296

Regulatory T Cells (Tregs) suppress host antitumor immunity
Behary et al. 2021 Nat. Commun. 12: 187

The diverse distribution and function of regulatory T cells (Tregs) ensures tissue and immune homeostasis.
Wang et al. 2020k Immunol Rev 295: 126-139

Systemic and local changes in nutrient availability and metabolite profile disrupt the abundance and functions of Tregs.
Wan…

References (Sources)

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4 + T cell subsets
Michalek et al. 2011 J Immunol 186: 3299-3303
Extrathymically generated Treg cells control mucosal Th2 inflammation.
Josefowicz et al. 2012
FOXP3 + regulatory T cells in the human immune system
Sakaguchi et al. 2010 Nature 10: 490
Review
Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor
Miyara et al. 2009 Immunity 30(6): 899- 911
Mitochondrial complex III is essential for suppressive function of regulatory T cells
Weinberg et al. 2019 Nature 565: 495-499
Molecular and Cellular Characterization of Human CD8 T Suppressor Cells
Xu et al., 2016
Regulatory T cells and immune tolerance
Sakaguchi et al. 2008
Review

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Regulatory T Cells (Tregs)

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