Facultative anaerobic bacteria, such as Enterobacteriaceae / Enterobacteria, may be capable of diverting nutrients away from the host by metabolizing fermentation products when oxygen is present
As the most abundant SCFA, acetate is produced by most enterobacteria from pyruvate via acetyl-CoA and also via the Wood–Ljungdahl pathway by acetogens
A wide range of human Diseases / Disorders are associated with a severe disruption of the balanced gut microbial ecosystem , often characterized by an expansion of facultative anaerobic Enterobacteriaceae
Enterobacteriaceae expansion may play an important role in the pathogenesis of human diseases and should be considered a microbial signature of intestinal dysbiosis
All members of the Enterobacteriaceae family are classified as glucose fermenters because they can metabolize glucose anaerobically. Within this family, maltose fermentation differentiates between different species of Proteus bacteria
In the healthy colon, the pathogen Enterobacteriaceae are a minor constituent of microbiota
In summary, Enterobacteria have the potential for either harmful pathogenic effects or for health-promoting functions
see also:
Acetate-producing bacteria