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Deoxynucleoside triphosphate (dNTP) / Nucleotide can be harmful outside cells and may cause cell death. To prevent damage, they must be neutralized. P2 receptors on almost all cells do this job. Purinergic signalling affects immune cells. It influences calcium mobilization. It affects actin polymerization. It impacts chemotaxis. It triggers mediator release. It aids cell maturation.
P2 receptors respond to ATP and are involved in modulating nervous system function
A unique subset of [lamina pro…