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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Signal transducer and activator of transcription 5 (STAT5)

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A “mammary gland specific nuclear factor” activated by prolactin was identified and designated Signal transducer and activator of transcription 5 (STAT5)
Gouilleux et al. 1994 EMBO J 13: 4361-4369
Wakao et al. 1994 EMBO J 13: 2182-2191
Liu et al. 1995a Proc Natl Acad Sci USA 92, 8831–8835

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Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue
Liu et al. 1995a Proc Natl Acad Sci USA 92, 8831–8835
Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response
Wakao et al. 1994 EMBO J 13: 2182-2191
Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription
Gouilleux et al. 1994 EMBO J 13: 4361-4369

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