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Antigenicity allows recognition of foreign proteins as nonself
Antigenicity, the first discriminatory function of the immune system, refers to the ability of antigens, typically peptides, to bind to and stimulate T and B cell receptors
Immunogenicity depends on two key factors: antigenicity and adjuvanticity.
The presence of exogenous or mutated Antigens can trigger an adaptive immune response from infected and malignant cells if the cells also emit adjuvant signals resulting from cell stress and cell death.
One type of [immune escape](brain://sRCpaB2n8lysEdlRaY…