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Biosynthesis & Polyamines / Polyamine
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With alfa-difluoromethylornithine (DFMO), the enzyme can be inhibited, and the polyamine concentration reduced. So: the inhibition of the polyamine transporter by AMXT1501 and the inhibition of the Ornithine Decarboxylase (ODC) by DFMO can, in principle, be viewed as an anti-tumor strategy
see also:
Cancer / Tumors & Polyamines / Polyamine
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