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Key features:
= a ring of proteins that seals apical epithelium; includes the integral membrane proteins occludin and claudin, in association with cytoplasmic Zonula Occludens (ZO) Proteins (Zoludins)
Occludin plays a role in regulating interactions between occludin and Zonula Occludens Protein-1 (ZO-1), which helps maintain a complete tight junction (TJ) complex and supports paracellular barrier function. Studies indicate that [short-chain fa…