Loading…

Medical Research Finder

Legal Notice
Privacy
Terms of Use

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

meRfi® AI Chat

Branching of N-glycans

Welcome to meRfi-GM!

Please register to continue your trial period!

meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.

Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.

Start your free trial and transform your understanding of the gut microbiota today!

(Login)

Navigation

Increased branching of N-glycans, mediated by beta-1,6-N-acetyl-glucosaminyltransferase V (MAGT5), can influence cell adhesion, migration, and metastasis of tumor cells.
Granovsky et al. 2000 Nat Med 6: 306-12
Varki et al. 2015
Hou et al. 2016 Faseb J 30: 4120-31
Mereiter et al. 2019 Cancer Cell 36: 6-16

Increased branching of N-glycans can directly inhibit T cell activation by increasing T cell receptor (TCR) clustering. This effect was attributed to interaction with [gale…

References (Sources)

Control of T cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis
Grigorian et al. 2007 J Biol Chem 282: 20027-35
Glycosylation Changes in Cancer.
Varki et al. 2015
Glycosylation in the era of Cancer-Targeted therapy: where are we heading?
Mereiter et al. 2019 Cancer Cell 36: 6-16
Review
Importance of membrane-proximal N-glycosylation on integrin β1 in its activation and complex formation
Hou et al. 2016 Faseb J 30: 4120-31
Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation
Demetriou et al. 2001 Nature 409: 733-9
Suppression of tumor growth and metastasis in Mgat5-deficient mice
Granovsky et al. 2000 Nat Med 6: 306-12

AI Chat

2/26/2026

Chat with our artificial intelligence:

Start chat!

Branching of N-glycans

Welcome to meRfi-GM!

Navigation

Contents

References (Sources)

AI Chat