meRfi®-GM
The Digital Textbook on Gut Microbiota and Beyond
CD11c (Integrin Alfa X (ITGAX))
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CD11c+ is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells / B Lymphocytes that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
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