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Recently, several hundred proteins were discovered that contained an Large clostridial toxins (LCTs)-like T domain, but in many cases lacked other hallmark features of traditional Large clostridial toxins (LCTs), and were found in bacteria other than clostridia
The massive expansion of T-domain homologs provided new insights into the molecular mechanisms of the still poorly understood process of Large clostridial toxins (LCTs) translocation
Large clostridial toxins (LCTs) are a…