Product Managers

meRfi® Microbiome can help microbiome‑based health and dietary supplement companies market a variety of products:

Relevant topics include positioning around functions such as “supports the immune system” or “for your daily well‑being.” In many products, live cultures are positioned without an explicit health claim (e.g., fermented dairy products, yogurt cultures). Explicit benefit claims often appear in professional materials, websites, or training content (e.g., “supports digestive health,” “supports immune health”).

Key topics relate to the use of authorized fiber / digestive health claims (e.g., “dietary fiber contributes to normal bowel function or increased stool frequency”). Communication uses terms such as “prebiotic fibres,” “food for your good gut bacteria,” and “dietary fibre” to connect prebiotics with microbiome storylines.

Relevant topics center on benefit wording, which is usually formulated restrictively; from a regulatory perspective, these products are often positioned at the interface between dietary supplements and medicinal products.

Typical claims such as “contributes to normal functioning of the immune system” are embedded into clear, consumer‑friendly messages while formally remaining bound to the approved wording. Manufacturers often combine several claims (e.g., immune support plus reduced fatigue) to create a broader benefit profile, but they must avoid statements about the treatment, cure, or prevention of disease, as these would constitute medicinal‑product advertising.

 

The curated, continuously updated evidence base on the gut microbiota and related health topics provides the complete scientific context in a modern, encyclopedia‑style format— including citations, study details, and structured summaries—and thereby supports product development, positioning, and evidence‑based communication.

 

The AI, which responds in two steps (RAG (vector search) and GraphRAG (knowledge‑graph query)), delivers comprehensive, consistent answers with fewer hallucinations, as well as contextualized, logically connected responses that can be used directly for market and product analyses, claim validation, and stakeholder communication.

Short-chain fatty acids (SCFAs), particularly butyrate, play a significant role in exerting anti-inflammatory effects

Micronutrients and Prebiotics

Micronutrients play an important role in influencing the composition and metabolic activity of gut microbiota

Synergistic Effects on Gut Microbiota

The concept of synergistic effects in gut health often involves the combination of prebiotics and probiotics, known as synbiotics

Guidelines and Position Papers on Microbiota-Based Therapies

Several guidelines and position papers have been developed by professional societies regarding microbiota-based therapies

Clinical Evidence for Probiotics in Inflammatory Bowel Disease (IBD)

Probiotics have been investigated for their potential benefits in managing inflammatory bowel disease (IBD)

What synbiotics are and how they differ from pro- and prebiotics

Synbiotics can be found in various forms, including synbiotic food products and supplements

Prebiotics and Irritable Bowel Syndrome (IBS)

Prebiotic treatments have been associated with fostering the growth of beneficial bacteria

... and more