meRfi®-GM
Commensal Bacteria / Commensalism
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Contents
A large number of commensal bacteria interact with the host's adaptive immune system. They induce microbe-specific T cells and antibodies. This interaction can benefit both host and microbe. It protects the epithelial barrier and offers bacteria a safe haven. However, it can also cause intestinal inflammation.
Two hypotheses have been proposed about this interaction: the presence of PRRs in host cells to recognize MAMPs and [Alarmins / Damage-associated m…
References (Sources)
- A secreted bacterial peptidoglycan hydrolase enhances tolerance to enteric pathogens
- Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells
- Host-gut microbiota metabolic interactions
- How gut microbes talk to organs: the role of endocrine and nervous routes
- Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease
- Mapping the T cell repertoire to a complex gut bacterial community
- Microbe-associated immunomodulatory metabolites: influence on T cell fate and function