meRfi®-GM
The Digital Textbook on Gut Microbiota and Beyond
Peptidoglycan (PGN)
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Contents
Gram-negative bacteria (GNB) have a distinct cell wall structure characterized by a thin peptidoglycan layer sandwiched between an inner cytoplasmic membrane and an outer membrane.
Gram-positive bacteria (GPB) characterized by a thick peptidoglycan layer in their cell wall, which retains the Crystal Violet stain in the Gram-staining procedure.
The human innate immune system responds to bacterial peptidoglycans (PG) from bacteria, whether they are [pathogens](brain://aKAC0T2fKU6Ss8xccKia4…
References (Sources)
- Bacterial peptidoglycan fragments differentially regulate innate immune signaling
- Integrative inflammasome activity in the regulation of intestinal mucosal immune responsesReview
- Interaction between microbiota and immunity in health and disease
- Peptidoglycan from the gut microbiota governs the lifespan of circulating phagocytes at homeostasis
- Peptidoglycan recognition by the innate immune system
- The struggle within: microbial influences on colorectal cancer
- Toll-like receptor signaling in colorectal cancer: carcinogenesis to cancer therapy