Loading…

Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Alzheimer's Disease (AD) & Tau Protein

Welcome to meRfi-GM!

Please register to continue your trial period!

meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.

Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.

Start your free trial and transform your understanding of the gut microbiota today!

tautangles (NFT) are present within the neurons
Naomi et al. 2022 Nutrients 14: 20

In Alzheimer's Disease (AD), phosphorylated Akt undergoes sulfhydration at C77 due to elevated hydrogen sulfide (H₂S) levels linked to IL-1beta-mediated inflammation. The sulfhydration of AKT initiates the phosphorylation of Tau by activating Glycogen synthase kinase-3 beta (GSK-3 beta)
Sen et al. 2020 Proc Natl Acad Sci USA 117(8): 4418-…

Alzheimer’s disease: phenotypic approaches using disease models and the targeting of tau protein
Lauretti & Praticò 2020 Expert Opin.Ther.Targ. 24: 319-330
Review
APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline
Montagne et al. 2020
Focusing on oligomeric tau as a therapeutic target in Alzheimer’s disease and other tauopathies
Rayman 2023 Expert Opinion on Therapeutic Targets 27(4-5): 269-279
Review
Probiotics for Alzheimer’s Disease: A Systematic Review
Naomi et al. 2022 Nutrients 14: 20
Review
Sulfhydration of AKT triggers Tau-phosphorylation by activating glycogen synthase kinase 3β in Alzheimer’s disease
Sen et al. 2020 Proc Natl Acad Sci USA 117(8): 4418-4427
The Role of Glycogen Synthase Kinase-3 (GSK-3) in Alzheimer’s Disease
Medina & Avila 2011 in: Physiological & neuro-psychology, biopsychology

12/16/2025