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Pyroptosis is a highly inflammatory form of programmed cell death distinct from apoptosis. It is characterized by cell swelling, membrane rupture, and the release of pro-inflammatory cellular contents.
Pyroptosis is mediated by the activation caspase-1 in response to various infection or stress signals. It is associated with the construction and activation of the NLRP3 inflammasome.
see also:
Caspase Recruitment Domains (CARDs)
[Caspases & Pyroptosis](brain://FaJuNTbyPUelbduS0uzX6g/CaspasesPyropt…