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Caspase-1 Activation
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Contents
Pyrin Mediates Caspase 1 Inflammasome Activation
Inflammasome-mediated caspase-1 activation occurs in macrophages, dendritic cells, epithelial cells
Natural cell death (Apoptosis) characterized by the activation of executioner caspases
Ellis & Horvitz, 1986
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References (Sources)
- A signaling pathway consisting of miR-551b, catalase and MUC1 contributes to acquired apoptosis resistance and chemoresistance
- Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
- Emerging inflammasome effector mechanismReview
- Genetic Control of Programmed Cell Death in the Nematode C. elegans
- Heat shock and HSP-70 regulate 5-FU- mediated caspase-1 activation in myeloid-derived suppressor cells and tumor growth in mice