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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Caspase-1 Activation

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Pyrin Mediates Caspase 1 Inflammasome Activation
Xu et al. 2014 Carcinogenesis 35(11): 2457-66

Inflammasome-mediated caspase-1 activation occurs in macrophages, dendritic cells, epithelial cells
Lamkanfi, 2011

Natural cell death (Apoptosis) characterized by the activation of executioner caspases
Ellis & Horvitz, 1986
…

A signaling pathway consisting of miR-551b, catalase and MUC1 contributes to acquired apoptosis resistance and chemoresistance
Xu et al. 2014 Carcinogenesis 35(11): 2457-66
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
Kanneganti et al. 2006 J Biol Chem 281: 36560–36568
Emerging inflammasome effector mechanism
Lamkanfi, 2011
Review
Genetic Control of Programmed Cell Death in the Nematode C. elegans
Ellis & Horvitz, 1986 Cell 44: 817-829
Heat shock and HSP-70 regulate 5-FU- mediated caspase-1 activation in myeloid-derived suppressor cells and tumor growth in mice
Pilot et al. 2020

12/16/2025