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The availability of fiber diminishes as the intestinal content moves from the proximal to the distal colon. This is potentially further exacerbated with Western diets due to their low fiber content. Consequently, the gut microbiota in the distal colon switches toward undigested peptides and proteins (exogenous, from the diet and endogenous from mucins) as an alternative Energy source.
Fermenting / Fermentation of dietary fiber by primar…