meRfi®-GM
ST2 receptor
Welcome to meRfi-GM!
meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
Navigation
Contents
The Interleukin-33 (IL-33) receptor, known as ST2, is found on many immune cells. It is crucial for type 2 immune functions. ST2 is also present on CD4 and CD8 T cells during type 1 responses.
When IL-33 binds, ST2 pairs with Interleukin-1 Receptor Accessory Protein (IL1RAcP). This activates NF-kB and Mitogen-activated protein kinases (MAPKs or MAP kinases) through the [M…
References (Sources)
- IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
- T-bet- and STAT4-dependent IL-33 receptor expression directly promotes antiviral Th1 cell responses
- Type-2 CD8+ T-cell formation relies on interleukin-33 and is linked to asthma exacerbations