meRfi®-GM
Interleukin-1 Receptor Accessory Protein (IL1RAcP)
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Contents
Interleukin-1 Receptor Accessory Protein (IL1RAcP) is a co-receptor that forms complexes with other receptors in the Interleukin-1 (IL-1) / Interleukin-1 family. It is particularly important for the signaling of Interleukin-33 (IL-33), a cytokine belonging to the IL-1 family
Interleukin-33 (IL-33) specifically binds to Interleukin 1 receptor-like 1 (IL1RL1), and when associated with Interleukin-1 Receptor Accessory Protein (IL1RAcP), it forms a heterodimeric receptor. The [Toll-interleukin-1 receptor (TIR) homology domain](brain://ae_SPSdgRUm0fyK-FLUQQA/Tollinterleukin1ReceptorTir…