TCRgamma/delta+ IELs

Activated TCRgamma/delta+ IELs have the ability to secrete cytokines and chemokines, which in turn activate TCRalfa/beta+ IELs. This process initiates a more robust adaptive immune response.
Lavelle et al. 2010 Mucosal Immunology 3(1): 17-28
Hoytema van Konijnenburg et al. 2017 Cell 171(4): 783-794
Montalban-Arques et al. 2018 Inflammatory Bowel Diseases 24(8): 1649-1659

see also:
Innate lymphoid cells (ILCs)
Intraepithelial Lymphocytes (IELS)
NOD-like receptors (NLRs)
RIG-I like receptors (RLR)
Toll-Like Receptors (TLRs)