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Helminths / Parasitic worms infect humans and animals, causing disease. These parasitic worms include Nematodes (roundworms), Cestodes (tapeworms), and Trematodes (flukes)
Simple mucin-type cancer-associated O-glycan structures, such as the Tn antigen (GalNAc-O-Ser/Thr), are expressed by certain helminth parasites. These antigens play a crucial role in various receptor–ligand interactions and are potential targets for immunotherapy.
The results of this study provide the first evidence of O-glycosylation pathways in…