meRfi®-GM
Biological effects / Functions & Propanoate Metabolism / Propionate / Propionic acid
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Contents
GPR41 is expressed in intestinal Enteroendocrine Cells (EEC), stimulating the release of glucagon-like peptide-1 (GLP-1) and peptide YY (PYY). PYY can regulate intestinal movement, affecting the absorption of nutrients in the intestine, and GLP-1 can regulate [satiety](brain://1Kd6g6-650CO1mVpI_…
References (Sources)
- Blockade of dendritic cell development by bacterial fermentation products butyrate and propionate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases
- Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial
- Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults
- Metabolism, Potential Applications and Underlying Mechanisms
- Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits
- The role of short-chain fatty acids in health and disease
- The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents