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Insulin stimulates the synthesis of fatty acids from e.g. glucose intermediates, known as de novo lipogenesis. Adipocytes are responsible for storing energy by accumulating cellular lipids. As part of this process, de novo lipogenesis occurs, which produces fatty acids that are later utilized for the synthesis of triacylglycerol. De novo lipogenesis is not the primary route for the subsequent synthesis of triacylglycerol in adipocytes; instead, triacylglycerols are formed from dietary fatty acids.