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3-oxolithocholic acid (3-oxoLCA) is a bile acid metabolite that plays a significant role in modulating the immune system, particularly in the gut.
Gut bacteria convert the secondary bile acid lithocholic acid into 3-oxolithocholic acid (3-oxoLCA). 3-oxoLCA has been identified as an inhibitor of T helper 17 (TH17) cell differentiation
The bile acid metabolite produced by gut bacteria 3-oxolithocholic acid (3-oxoLCA) inhibits Th17 cell differentiation. The admini…