Loading…

Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Interleukin-22 (IL-22) & Signal transducer and activator of transcription 3 (STAT3)

Welcome to meRfi-GM!

Please register to continue your trial period!

meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.

Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.

Start your free trial and transform your understanding of the gut microbiota today!

IL-22 confers protection via the STAT3 signal transduction pathway by inducing the production of other antimicrobial peptides such as BD-2, BD-3, Calcium-Binding Protein A7 (S100A7), [Calcium-Binding Prot…

Cytokine-Mediated Crosstalk between Immune Cells and Epithelial Cells in the Gut
Mahapatro et al. 2021
Review
IL-22 Increases the Innate Immunity of Tissues
Wolk et al. 2004 Immunity 21: 241-254
IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular diﬀerentiation, and mobility in keratinocytes: A potential role in psoriasis
Wolk et al. 2006 Eur. J. Immunol. 36: 1309-1323
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
Liang et al. 2006 J. Exp. Med. 203: 2271-2279
Interleukin-22 mediates early host defense against attaching and eﬀacing bacterial pathogens
Zheng et al. 2008 Nat. Med. 14: 282-289
Lactobacillus Accelerates ISCs Regeneration to Protect the Integrity of Intestinal Mucosa through Activation of STAT3 Signaling Pathway Induced by LPLs Secretion of IL-22.
Hou et al. 2018 Cell Death Differ. 25: 1657–1670
STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
Pickert et al. 2009 J. Exp. Med. 206: 1465-1472

5/29/2026