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Interleukin-22 (IL-22) can be leased by Innate lymphoid cells (ILCs) and T cells / T lymphocytes. Innate lymphoid cells (ILCs) and T cells / T lymphocytes localize to distinct microanatomic niches during Citrobacter rodentium infection. There are spatiotemporal differences in the production and action of Interleukin-22 (IL-22) by Innate lymphoid cells (ILCs) and T cells / T lymphocytes during infection and reveal an indispensable role for IL-22-producing T cells in the protection of the intestinal crypts.
ILC-derived IL-22 activated [STAT3](brain://HitA…