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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Vitamin D receptor (VDR)

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Immunomodulatory and anti-inflammatory function; stimulation of production of antimicrobial proteins such Cathelicidin)
D’Aldebert et al. 2009 Gastroenterology 136: 1435-1443
Wallace et al. 2010 J. Steroid Biochem. Mol. Biol. 120: 137-148
Ihunnah et al. 2011

Dimer: VDR/RXR

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References (Sources)

Bile salts control the antimicrobial peptide cathelicidin through nuclear receptors in the human biliary epithelium
D’Aldebert et al. 2009 Gastroenterology 136: 1435-1443
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota
Wang et al. 2016 Nat Genet 48: 1396-1406
Nuclear receptor PXR, transcriptional circuits and metabolic relevance
Ihunnah et al. 2011
Review
The PXR is a drug target for chronic inflammatory liver disease
Wallace et al. 2010 J. Steroid Biochem. Mol. Biol. 120: 137-148

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12/16/2025

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