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Alzheimer's disease (AD)
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Contents
Alzheimer's Disease (AD) is the most common neurodegenerative disorder, characterized by the extracellular deposition of amyloid-beta (Aβ) and intracellular accumulation of hyperphosphorylated aggregated tau. It is a chronic, age-related progressive neurological disorder accounting for approximately 80% of dementia cases globally.
Alzheimer's disease (AD) cases are rising globally, doubling every 20 years, with neurological pathologies develop…
References (Sources)
- 2021 Alzheimer's disease facts and figures
- Alzheimer's disease research: the future of BACE inhibitors
- AXS-05: an investigational treatment for Alzheimer’s disease-associated agitation
- Gut Microbiota and Dysbiosis in Alzheimer’s Disease: Implications for Pathogenesis and TreatmentReview
- The Endocannabinoid System: A Bridge between Alzheimer’s Disease and Gut Microbiota
- Twenty years of the Alzheimer’s disease amyloid hypothesis: A genetic perspective
- Western diet as a trigger of Alzheimer’s disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration