meRfi®-GM
Defense Systems / Defense Mechanisms
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Pathogens have led to the development of various defense strategies in cells, known as cell-autonomous innate immunity. Bacteria possess a wide range of defense systems to protect against bacterial viruses, or phages. Recent research has revealed that innate immunity shares similarities across different organisms, with components of eukaryotic innate immunity also found in bacteria. This includes pathways such as cGAS-STING, gasdermins, and [Radical S-adenosyl methionine domain-containing protein 2](brain…
References (Sources)
- Antibacterial Weapons: Targeted Destruction in the Microbiota
- Bacterial antagonism in host-associated microbial communities
- Bacteriocins — a viable alternative to antibiotics?
- Contact-Dependent Interbacterial Antagonism Mediated by Protein Secretion Machines
- Innate immunity: the bacterial connection
- Microbial Flora Drives IL-22 Production in Intestinal NKp46+ Cells that Provide Innate Mucosal Immune Defense