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cGAS-STING Pathway

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The cGAS -STING pathway is a crucial part of the immune system that is responsible for recognizing cytosolic DNA and triggering an immune response (e.g., interferon response).

The system involves the production of cyclic nucleotides in response to specific stimuli.
Liu et al. 2022g Front. Immunol. 12: 814709

see also:
cGAS like receptors (cGLRs)
Cyclic dinucleotides (cDNs)
Cyclic GMP-AMP synthase (cGAS)