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NF kappa B (NFKB) / NFKB Family
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Contents
NF kappa B (NFKB) / NFKB Family is a stimulus-responsive inducible transcription factor with cytoplasmic localization in the steady state. A reasonable proxy for NFKB activation in live cells is the relative nuclear concentration (i.e., the ratio of nuclear to total cellular concentration), where it binds to transcription genes
Context-specific induction of other NF kappa B (NFKB) factors also tune inflammatory genes
Mainly [RelA:…
References (Sources)
- Microbes in gastrointestinal health and disease
- NF-KB dynamics in the language of immune cells
- Predominant Activation of JAK/STAT3 Pathway by Interleukin-6 Is Implicated in Hepatocarcinogenesis
- Role of the NF-κB system in context-specific tuning of the inflammatory gene response
- The G-protein coupled bile acid receptor Gpbar1 (TGR5) negatively regulates hepatic inflammatory response through antagonizing Nuclear Factor κB
- The microbiome and cytosolic innate immune receptors
- Trimethylamine N-Oxide Promotes Vascular Inflammation Through Signaling of Mitogen-Activated Protein Kinase and Nuclear Factor-κB