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Inflammation / Inflammatory Diseases & Neutrophils / Neutrophilic Granulocytes
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Neutrophils / Neutrophilic Granulocytes are the most common immune cells found where there is inflammation. They were once thought to only have the job of attacking and killing harmful invaders using three main methods: swallowing and destroying them with oxidative stress, releasing substances from their granules, and creating structures called neutrophil extracellular traps (NETs)
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References (Sources)
- Degradation of human antimicrobial peptide LL-37 by Staphylococcus aureus-derived proteinases
- Increased dietary manganese impairs neutrophil extracellular trap formation rendering neutrophils ineffective at combating Staphylococcus aureus
- Mitochondrial calcium uniporter affects neutrophil bactericidal activity during Staphylococcus aureus infection
- Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis
- Neutrophil extracellular traps enhance macrophage killing of bacterial pathogens
- Protein chlorination in neutrophil phagosomes and correlation with bacterial killing
- Staphylococcus aureus strains lacking D-alanine modifications of teichoic acids are highly susceptible to human neutrophil killing and are virulence attenuated in mice