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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

CD284 (Toll-Like Receptor 4 (TLR-4)) / MYD88 / NFKB signaling pathway

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CD284 (Toll-Like Receptor 4 (TLR-4)) is an exception as it is the only Toll-Like Receptors (TLRs) that utilizes both MyD88-dependent and TRIF-Dependent Pathway
Chen et al. 2019m J. Biomed. Sci. 26: 90

Toll-Like Receptor 4 (TLR-4) signaling
The agonists Lipopolysaccharides (LPS) and RSV F protein lead to dimerization. The two adapter molecules, [TIR domain containing adaptor protein (…

Beyond defense: regulation of neuronal morphogenesis and brain functions via Toll-like receptors
Chen et al. 2019m J. Biomed. Sci. 26: 90
Review
Recognition and signaling by Toll-like receptors
West et al. 2006 Annu Rev Cell Dev Biol. 22: 409-37
Review
Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4
Venkatesh et al. 2014 Immunity 41: 296-310
Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function
Abreu 2010 Nature Rev. Immunology 10: 131
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta
Kagan et al. 2008 Nat. Immunol. 9: 361-368
Ubiquitin signalling in the NF-κB pathway
Chen 2005 Nat. Cell. Biol. 7: 758-65

5/29/2026