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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

G-Protein Coupled Receptor 41 (GPR41) & Propanoate Metabolism / Propionate / Propionic acid

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GPR41 and GPR43 can be efficiently activated by acetate, Propionate / Propionic acid, Butyrate / Butyric acid and other SCFAs
Brown et al. 2003 J. Biol. Chem. 278: 11312-11319

Propionate / Propionic acid was the most potent agonist for both [GPR41](brain://3i5Jh_jcPkCkCMAu4O3LUg/GproteinCoupledReceptor41gpr41ffar3…

Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation
Le Poul et al. 2003
The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids
Brown et al. 2003 J. Biol. Chem. 278: 11312-11319

5/29/2026