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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Curli

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Curli are highly conserved surface organelles that mediate binding of bacteria to soluble matrix proteins
Olsén et al. 2019 Nature 338: 652-655

Some bacteria that produce these curli ﬁbers are recognized by the same Toll-like receptor as the Beta-amyloid 42 peptide that accumulates in Alzheimer's Disease (AD)
Zhao et al. 2015 J Alzheimers Dis Parkinsonism 5: 177
Tursi & Tükel 2018 Microbiol. Mol. Biol. Rev. 82: e00028-18
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References (Sources)

Curli-containing enteric bioﬁlms inside and out: matrix composition, immune recognition, and disease implications
Tursi & Tükel 2018 Microbiol. Mol. Biol. Rev. 82: e00028-18
Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans
Chen et al. 2016c Sci Rep. 6: 34477
Fibronectin binding mediated by a novel class of surface organelles on Escherichia coli
Olsén et al. 2019 Nature 338: 652-655
Microbial sources of amyloid and relevance to amyloidogenesis and Alzheimer’s disease (AD)
Zhao et al. 2015 J Alzheimers Dis Parkinsonism 5: 177

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Curli

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