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Several BA-derived metabolites play a role in intestinal immunity affecting IBD and CRC.
Elevated serum levels of hydrophobic bile acids such as CDCA and DCA have been linked to colon cancer, gallstones, and other gastrointestinal (GI) diseases
Increased levels of secondary bile acids are associated with specific diseases of the GI system
Ridlon et al. 2016 Gut Microbes 7: 22–39