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It is likely that Adherent-Invasive E. Coli (AIEC) are able to proliferate more effectively in hosts with defective innate immunity. They are associated with the ileal Mucosa / Mucous membrane in Crohn's disease (CD)
Adherent-Invasive E. Coli (AIEC) are able to invade intestinal epithelial cells, replicate intracellularly (e.g., in macrophages), and induce TNF production from [macrophages](brain://ckHBwX0eQUGyP8URvNQj3Q/Macrophag…