Mucin Degrading Bacteria

These microorganisms have evolved to break down and utilize the mucus layer that lines the intestinal tract

The presence of mucus-degrading bacteria is crucial for maintaining mucosal homeostasis. However, an imbalance in their abundance or activity can lead to potential health issues
Overbeeke et al. 2022 Nutrients 14(18): 3802

Lack of dietary fiber results in erosion of the mucosal layer, suggested to be a result of increased mucus-degrading gut bacteria.
Overbeeke et al. 2022 Nutrients 14(18): 3802

Both chronic and intermittent fiber deficiency promotes enrichment of mucus-degrading bacteria
Desai et al. 2016 Cell 167: 1339–1353

Akkermansia muciniphila and B. caccae are able to degrade MOGs in vitro.
Desai et al. 2016 Cell 167: 1339–1353

Ruminococcus as well as co-occurring Akkermansia, both known to comprise species able to degrade mucins
Derrien et al. 2004 Int J Syst Evol Microbiol. 54: 1469–1476

see also:
Akkermansia muciniphila
Bacteroides thetaiotaomicron
Intestinal Epithelial Barrier / Mucosal Barrier / Mucus Layer
Leaky Gut Syndrome / Leaky Gut