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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Interleukin 1 receptor-like 1 (IL1RL1)

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Interleukin 1 receptor-like 1 (IL1RL1) is expressed on human Group 2 ILCs (ILC2) in blood, lung, tonsil
Meininger et al. 2020 Trends in Immunology 41: 902

The Intestine / Gastrointestinal tract (Gut/GIT) releases ST2 during GVHD damage (Vander et al. 2013 N Engl J Med. 369(6): 529-539) (intestine GVHD). It is the ligand for the alarmin Interleukin-33 (IL-33) and Reg III alfa, an antimicrobial peptide produced by [Paneth cells](brain://08Ip-1Ci6Ey…

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ST2 as a marker for risk of therapy-resistant graft-versus-host disease and death
Vander et al. 2013 N Engl J Med. 369(6): 529-539
ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease
Zhang et al. 2015a Sci Transl Med. 7(308): 308ra160
Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease
Zhao et al. 2018e J Clin Invest. 128(11): 4970-4979
Tissue-Specific Features of Innate Lymphoid Cells
Meininger et al. 2020 Trends in Immunology 41: 902
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